FDA: Acetaminophen doses over 325 mg might lead to liver damage

by Rachel Baker on January 15, 2014

The FDA is making recommendations that apply to prescription combination drugs containing acetaminophen. An over-the-counter drug recommendation will be addressed in a future regulatory action.

You’re in pain after surgery, and your doctor prescribes you Vicodin, or maybe Percocet. But when you get home, the pain hasn’t subsided and you decide to pop some Extra Strength Tylenol.

Unknowingly, you may have just taken more of the drug acetaminophen than is safe.

Acetaminophen is often used in pain medications with opioids such as oxycodone (Percocet), hydrocodone (Vicodin) and codeine (Tylenol with Codeine). These are called combination drugs, and the Food and Drug Administration is asking doctors to stop prescribing those that have more than 325 mg of acetaminophen per dose.

The FDA says no data show that taking more than that amount provides enough benefit to outweigh the risk of liver damage.

Check out the remainder of the article here:
http://www.cnn.com/2014/01/15/health/fda-acetaminophen-dosage/

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